Clindamycin 1) Chemical Name: * methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate) 2) Drug name and manufacturing business: * The dose name is Cleocin. Clindamycin is manufactured by several unalike companies which include Teuto, Ranbaxy, and Stiefel. 3) Mechanism of Action: * Clindamycin is employ to compensate stern infections ca intentd by anaerobic bacteria. Clindamycin is withal prescribed to treat malignant infections due to strains of streptococci, pneumococci, and staphylococci. Clindamycin is an anti-parasitic drug that is prescribed to treat toxoplasmosis. Also, a great deal it is utilize as investigational treatment for active PCP pneumonia. It in any case treats respiratory tract infections. If you are allergic to penicillin, or should non use penicillin check to a medical student, then clindamycin should be employ specifically for these patients. Due to a risk of colitis, according to the warning on the prescription, a doctor should choose former(a) less cyanogenic alternatives if the infection isnt as serious. An example would be erythromycin. To lessen the cherish the sustainability of Cleocin, it should barely be used to resume or go on infections and fungi that are emphatically caused by vulnerable bacteria. 4) set apart or wide-cut Spectrum: Narrow Spectrum 5) What organisms is this antibiotic for? * Aerobic positive cocci, including: staphylococcus aureus, Staphylococcus epidermidis, when tested by in vitro methods close to staphylococcal strains in the beginning resistant to erythromycin rapidly cause resistance to clindamycin, streptococci (except Streptococcus faecalis), Pneumococci. * anaerobic gram-negative bacilli, including: genus Bacteroides species (including Bacteroides fragilis class and Bacteroides melaninogenucus group), Fusobacterium species. * Anaerobic gram-positive non spore forming b acilli, including: Propionibacterium, Eubact! erium, Actinomyces species. Anaerobic and microaerophilic gram-positive cocci, including: Peptococcus species, Peptostreptococcus species, Microaerophilic streptococci. 6) How is it administered? Clindamycin push aside be administered in 3 mixed steps. Also, for the best results, toy with to take the antibiotic on a daily basis. * by word of mouth Take either with a meal or without a meal. Remember that if you are experiencing stomach pains, take with food. Taking it with a full glass of water is also optional. * Vaginal coat - demarcation that the cream can only be used in this area. It may cause burning, and above all do not have sexual intercourse while victimization this drug. * peel off Application Not to be interpreted by mouth. Lotion should be agitate prior to application. reassign pledget from foil and immediately throw away. take proper hygiene and wash hands before and afterward use. Apply only a thin strip of jelly to avoid irritation. Bandages, mak e-up, etc should not be applied until consulting a doctor for advice. 7) Any toxicities, or side effects? Â Â Â Â Â Â Â Â Abdominal pain, pseudomembranous colitis, esophagitis, nausea, vomiting and diarrhea.
generalized lenient to moderate morbilliform-like (maculopapular) skin rashes, Vesiculobullous rashes, urticaria, have been find during drug therapy. lofty instances of erythema muttiforme, some resembling Stevens-Johnson syndrome, and a few cases of anaphylactoid reactions have also been reported. sour and abnormalities in liver function tests have been observed during clindamycin therapy. fugitive neutropenia (leukopenia) and eosinophilia have been reported. Clindamycin has! been shown to have neuromuscular blocking properties that may kindle the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Opposition has been corroborate betwixt clindamycin and erythromycin. Do not take these antibiotics at the aforesaid(prenominal) time. References: 1) Retrieved February 22, 2006, from MedlinePlus Drug entropy net situation: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682399.html#brand-names 2) Retrieved February 22, 2006, from ADAP drugs Web aim: http://www.atdn.org/access/drugs/clin.html 3) Retrieved February 22, 2006, from clindamycin normally used music for HIV & AIDS patients Web website: http://www.hivdent.org/drugs/clindamycin.htm 4) Retrieved February 22, 2006, from medicament instructions for clindamycin Web site: http://www1.va.gov/visn10/CincyMedSheets/Clindamycin.htm 5) Retrieved February 22, 2006, from Clindamycin Web site: http://www.clindamycin.com / If you want to get a full essay, enunciate it on our website:
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